What is the more function of Genistein?
Published:2023-05-24 Views：432
What is the more function of Genistein?
Ovarian cancer
Inhibitory effect of genistein and daidzein on ovarian cancer cell growth.Five ovarian cancer cell lines from Stage IIIC disease were evaluated. Sulforhodamine B and colony formation assays were used to analyze growth inhibitory effects of genistein and daidzein alone and with cisplatin, paclitaxel or topotecan. Cisplatin and topotecan combined with genistein resulted in a mostly additive effect, paclitaxel was slightly less than additive. We demonstrate an inhibitory effect of genistein on ovarian cancer cell growth.
Prostate cancer
Genistein enhances the efficacy of cabazitaxel chemotherapy in metastatic castration-resistant prostate cancer cells.
Ebola virus natural treatment? not yet
Arch Virol. 2012. Inhibition of Lassa virus and Ebola virus infection in host cells treated with the kinase inhibitors genistein and tyrphostin. Arenaviruses and filoviruses are capable of causing hemorrhagic fever syndrome in humans. Limited therapeutic and/or prophylactic options are available for humans suffering from viral hemorrhagic fever. In this report, we demonstrate that pre-treatment of host cells with the kinase inhibitors genistein and tyrphostin AG1478 leads to inhibition of infection or transduction in cells infected with Ebola virus, Marburg virus, and Lassa virus. In all, the results demonstrate that a kinase inhibitor cocktail consisting of genistein and tyrphostin AG1478 is a broad-spectrum antiviral that may be used as a therapeutic or prophylactic against arenavirus and filovirus hemorrhagic fever.
Note: This study did not test whether administering genistein orally would cure ebola. I am also not aware of any such human studies regarding natural treatment for ebola.
Hot flashes, and menopause
Genistein and other flavonoids do not appear to have a significant effect in reducing the severity of hot flashes, at least not as much as estrogen.
#Genistein
