Is alpha-lipoic acid safe?

Alpha-lipoic acid is POSSIBLY SAFE for most adults when taken by mouth , when used intravenously or when applied to the skin. People taking alpha-lipoic acid by mouth might get a rash. People at risk for thiamine deficiency should take a thiamine supplement.

People with diabetes should be careful to check their blood sugar levels because alpha-lipoic acid might lower blood sugar.

What is the Special Precautions & Warnings for Alpha-lipoic acid?
Pregnancy and breast-feeding: Not enough is known about the use of alpha-lipoic acid during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Diabetes: Alpha-lipoic acid can decrease blood sugar levels. Your diabetes medications might need to be adjusted by your healthcare provider.

Excessive use of alcohol/thiamine deficiency: Alcohol can lower the amount of thiamine (vitamin B1) in the body. Taking alpha-lipoic acid when there is a shortage of thiamine might cause serious health problems. If you drink a lot of alcohol and take alpha-lipoic acid too, you should take a thiamine supplement.

Thyroid disease: Taking alpha-lipoic acid might interfere with treatments for under-active or over-active thyroid.

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