What is the biological importance of genistin?
1)Its estrogenic activity:
Removal of genistin or genistein from the diet caused tumors to regress.
2)Its antiviral activity:
Genistin and other isoflavones are demonstrated to be bioactive within the neonatal intestine and may reduce the severity of rotavirus infections; genistin alone shows inhibition of the viral infectivity by 40-60%.
3)Its bone metabolism:
It is also revealed that genistin has a strong bone loss preventive activity on experimental rats.
Genistin is also converted to a more familiar genistein, thus, the biological activities including antiatherosclerotic, estrogenic and anticancer effects are analogous.
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